Oxygen Club of California Workshop.

Venue: Ferrero Foundation, Via Vivaro 49, Alba (CN), Italy

9:00 Welcome to Participants

9:15 Opening remarks: Enrique Cadenas and Giuseppe Poli

9:30 – 10:15 KEYNOTE LECTURE (1)

Chair: Josiane Cillard, José Viña "Sarcopenia: an unsolved problem in gerontology and geriatrics. From molecular approaches to therapeutics"

SESSION I (2)

Chairs: Matilde Maiorino, Juan Sastre

10:30 – 11:00 Manuel Serrano “An integrated view of oxidative damage and cellular senescence.”

11:00 – 11:30 Kelvin Davies "Failure of proteostasis and adaptive homeostasis in aging"

11:30 – 12:00 Henry Forman “Aging and susceptibility to oxidative injury”

12:00 – 12:30 Tilman Grune “Possible role of protein aggregates in metabolic diseases”

12:30 – 13:00 Zhigang Liu "Redox Biology in the neuroprotection of methionine restriction on cognitive deficits"

13:00 – 14:30 Light Lunch

(1) Lester Packer Lecture

(2) Mario Dianziani's Session

SESSION II (3)

Chairs: Hüveyda Başağa, Federico Pallardó

14:30 – 15:00 Giovanni Mann “Nrf2-regulated redox signaling in cerebral ischemia-reperfusion injury”

15:00 – 15:30 Anne Nègre-Salvaire “Lipid peroxidation-derived aldehydes and premature placental aging in pathological pregnancies”

15:30 – 16:00 Giuseppe Valacchi “Cutaneous SRB1 involvement in extrinsic aging”

16:00 – 16:30 Leo Rodriguez-Mañas “Aging, nutrition, and frailty"

16:30 – 17:00 Cesar Fraga “Polyphenols for a healthy living; from your dinner to your cells nitric oxide bioavailability”

17:00 – 18:00 Round Table Discussion Enrique Cadenas, Patricia Oteiza, Fulvio Ursini “Oxidants and antioxidants in aging”

18:00 – 18:15 Closing remarks

20:30 Gala dinner (speakers, chairs and guests)